052 Identification of pathogenic T cell subsets in human alopecia areata

Immunohistochemical analysis of T-cell subsets in the inflammatory infiltrates of alopecia areata and its comparison with androgenetic alopecia

Background: Androgenic hair loss (AGA) and alopecia areata (AA) are common conditions which sometimes are histologically difficult to differentiate. This study was conducted to detect differentiating features of these two disorders with IHC analysis of T-cell subsets in the inflammatory infiltrates of alopecia areata and androgenetic alopecia. Methods: This cr...

Alopecia areata.

n engl j med 367;3 nejm.org july 19, 2012 279 methacin should be used in addition to pancre­ atic stents in high­risk patients. However, post hoc analysis of our trial suggests that indometha­ cin may obviate the need for prophylactic pan­ creatic stent placement (unpublished data), and we therefore agree with Baron et al. that com­ parative effectiveness studies of indomethacin and pancreatic ...

Alopecia areata.

Alopecia areata is a frequent cause of hair loss. The origin of disease is not fully understood. However there are indications for a T-cell mediated autoimmune process. Genetic, immunologic and psychologic factors are important for the outbreak of disease. Most patients show localized patches of acute hair loss, where regrowth is observed spontaneously or with simple topical treatment within fe...

Alopecia Areata

Management of alopecia areata

Epithelial Sciences, School of Translational Medicine, University of Manchester, Manchester Jackson Laboratory, Bar Harbor, ME, USA Department of Dermatology, China-Japan Union Hospital of JiLin University, Chang Chun, People’s Republic of China Department of Dermatology, University of Lübeck, D-23538 Lübeck, Germany Skin Disease Research Centre, Division of Dermatology, Vanderbilt Medical Cent...